Congenital Heart Disease
Clinical investigations examining the role of 3D echocardiography
in patients with congenital heart disease
have emphasized the unique perspective provided by
3D imaging and the versatility of the technique in
patients with simple defects or complex conditions
and in the postoperative state.115,116 Three-dimensional
echocardiography, using both reconstruction
methods and RT3D, has been used to detect several
forms of congenital heart disease. The ability to record
and analyze the entire cardiac structure and the ability
to display complex spatial relationships are potential
advantages of 3D imaging over 2D echocardiography.
In addition, the decreased examination time afforded
by RT3D echocardiography may reduce the need for
sedation in some children.116
In patients with atrial septal defects, 3D echocardiography
can record the size and shape of the defect. It
also can show the precise location of the defect and
the extent of residual surrounding tissue. In patients
with secundum atrial septal defects (Figure 11, video
clip 13), the extent of the retroaortic rim often determines
the feasibility of repair with percutaneous closure
devices. Three-dimensional echocardiography
also has been used after atrial septal defect closure to
evaluate the success of the procedure and identify the
origin of residual shunting.117 In patients with ventricular
septal defects, the ability to interrogate the entire
septum is frequently cited as an advantage of the 3D
technique.118,119 A novel application of 3D imaging in
patients with ventricular septal defects involves using
offline reconstruction to measure the shape and size of
the color flow jet, which allows for accurate measurement
of the magnitude of shunting in patients with
isolated ventricular septal defects.119
Various 3D echocardiographic techniques have
been used to evaluate RV and LV size and function in
patients with congenital heart disease. The approach
to the LV is similar to that described previously and
permits quantification of dimension, volume, mass,
and ejection fraction.120 Owing to the ellipsoidal shape
of the LV, the advantages of 3D over 2D echocardiographic
techniques are limited, because simple geometric
assumptions can be used to calculate LV volumes;
however, the RV’s asymmetrical shape
invalidates the simple geometric assumptions used for
LV volume calculations. In this case, the ability to
record and analyze the entire chamber rather than
relying on simplifying assumptions has proven
superior.48 In patients with congenital heart diseases
that involve RV pathology, 3D echocardiography correlates
well with MRI for the measurement of RV
volume.48,121,122
Three-dimensional echocardiography has been
successfully applied to the detection and assessment
of several anatomic defects. For example,
the circumferential extent and severity of discrete
subaortic membranes have been successfully visualized
with 3D echocardiography.119,120 With the
apical view, a unique en face image of the membrane
can be recorded, which permits analysis of
the effective orifice area and the dynamic nature
of the defect. Congenital malformations of the
mitral valve also have been assessed with 3D
echocardiography.80 The complex nature of these
defects can make a thorough anatomic evaluation
difficult. In such cases, the perspective provided
by 3D echocardiography can provide a complete
preoperative assessment of the extent and severity
of the valvular abnormality.
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